Study of the Neurophysiology of Central Fatigue

Abstract

Specific Aims: 1) To identify and characterize the functional neuroanatomic networks most strongly correlated with objective cognitive fatigue using event related potentials (ERPs). 2) To determine the neurophysiologic mechanisms underlying objective cognitive fatigue using the variable signal plus ongoing activity (VSPOA) model. 3) To investigate the relationship of GABAergic and glutamatergic neural transmission to objective cognitive fatigue and network pathology.

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Document Details

Document Type
Technical Report
Publication Date
Nov 05, 2014
Accession Number
ADA621838

Entities

People

  • Benzi M Kluger
  • Donald Rojas
  • Lauren Krupp
  • Mingzhou Ding
  • Roger Enoka

Organizations

  • University of Colorado Boulder

Tags

Communities of Interest

  • Biomedical

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  • Brain
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  • Neurology
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Fields of Study

  • Psychology

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Neuroscience