Micro/nano-particles and Cells: Manipulation, Transport, and Self-assembly
Abstract
Technologies that control nano- and micron-sized inert as well as biological materials are crucial to realizing engineered systems that can assemble, transport, and manipulate objects at these length scales. Two principles, (a) the domain wall structure of patterned magnetic structures and (b) the superparamagnetic properties of nanoparticles, were used to apply directed forces that maneuver, transport, sort and configure these tiny entities on a platform. Convenient, remotely activated, changes to the local energy landscape of the platform that were developed underlie the ability to, a) generate high (10,000 T/m) local field gradients, b) selectively apply femto- to pico-Newton scale forces to objects with designed magnetic signatures and c) direct these forces along desired pathways. A broad range of problems, both fundamental and applied, also benefited from control over the stochastic (Brownian) trajectories of trap-confined micro- and nano-particles. The projects ranged from activation of soft confinement barriers through creation of novel time-orbiting magnetic potentials that provide a new framework to stabilize intricate and design-specific behavior of interacting magnetic dipoles, formation of magnetic colloidal rotor pumps actuated within microfluidic channels, and the high-throughput transfection of genes into living cells for screening cellular heterogeneity.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 23, 2014
- Accession Number
- ADA621840
Entities
People
- R. Sooryakumar
Organizations
- Ohio State University