Treatment of Pain and Autonomic Dysreflexia in Spinal Cord Injury with Deep Brain Stimulation

Abstract

This project is a study of electrical deep brain stimulation (DBS) as a method for treating pain and autonomic dysreflexia in patients with chronic spinal cord injury (SCI). It is collaboration between the University of Miami and the Miami Veterans Administration Hospital. The first year was taken up with obtaining regulatory approval consecutively from the FDA and from the IRBs of the two sites. In the second year (report year), two subjects were recruited. The first subject, with a complete cervical (C5) injury, underwent surgery and is now in the 20th week of the 52 week study. No serious adverse effects were observed, but pain has not significantly changed. Protocols (FDA and IRB) were modified to allow inclusion of lower thoracic injury. This should increase the rate of recruitment. The surgery for the second subject, who has an incomplete thoracic (T10) injury, has been delayed until 5 November 2014.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2014
Accession Number
ADA622286

Entities

People

  • Jonathan R. Jagid :ian D.

Organizations

  • University of Miami

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Department Of Defense
  • Diseases And Disorders
  • Electric Stimulation Therapy
  • Electronic Mail
  • Health Services
  • Hospitals
  • Information Operations
  • Pain
  • Quality Of Life
  • Spinal Cord
  • Spinal Injuries
  • Thoracic Injuries
  • Universities
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Neurotrauma and Rehabilitation Medicine.