Prazosin Augmentation of Outpatient Treatment of Alcohol Use Disorders in Active Duty Soldiers with and without PTSD

Abstract

This project is a 12-week randomized controlled trial (RCT) of prazosin for AUD in 200 OIF/OEF soldiers both with and without comorbid PTSD enrolled in the Alcohol and Substance Abuse Program (ASAP) at Madigan Health Care System/Joint Base Lewis McChord. The aims of this trial are 1) to determine prazosin's efficacy for AUD in OIF/OEF soldiers participating in outpatient AUD treatment and 2) to determine if the presence of PTSD affects prazosin efficacy for AUD. In the first year of the study, the protocol was extensively review and recently approved by the VA Puget Sound IRB. This approval was necessary before the Madigan IRB would review the protocol. Madigan IRB has now accepted the study's application and we anticipate their approval by end of November 2013; this would allow an early December 2013 start of participant randomization.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
ADA622633

Entities

People

  • Murray A. Raskind

Organizations

  • Seattle Institute for Biomedical and Clinical Research

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Active Duty
  • Alcohol Consumption
  • Biomedical Research
  • Combat Areas
  • Combat Operations
  • Data Analysis
  • Department Of Defense
  • Diseases And Disorders
  • Electronic Mail
  • Health Care
  • Health Services
  • Information Operations
  • Instructions
  • Military Operations
  • Puget Sound

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.