Inactivation of Bacillus Anthracis Spores Using Carbon Nanotubes
Abstract
The Specific Aims of the project were to investigate: 1) the effect of single-walled carbon nanotubes (SWNTs) with different surface groups on the inactivation of B. anthracis spores; 2) the effect of SWNTs coupled with near-infrared (NIR) on B. anthracis spores; 3) the effect of SWNTs in combination with antimicrobial chemicals on inactivation of B. anthracis spores; 4) the effect of CNTs coated surfaces on the inactivation of B. anthracis spores; 5) the mechanisms of the inactivation effects of SWNTs to B. anthracis spores. Results of findings and their significance: We found that: 1) SWNTs were effective in inactivating B. anthracis cells, but not effective to B. anthracis spores. However, SWNTs can inhibit the biofilm formation from B. anthracis spores in suspension; 2) SWNTs coupled with oxidizing agents or near infrared laser enhanced its effect to inactivate B. anthracis spores; 3) Multi-well CNTs (MWNTS)-coated surfaces enhanced the attachment of B. anthracis spores, when in combination with natural peptide nisin, it can inhibit the biofilm formation from B. anthrancis spores. Overall, the project has resulted in 8 peer reviewed journal publications, 3 M.S. graduate student theses, a number of national conference presentations and student presentations/awards at college, university and local/regional conferences.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 30, 2014
- Accession Number
- ADA623023
Entities
People
- Liju Yang
Organizations
- North Carolina College