Nonlinear Analysis of Experimental Measurements 7.6. Theoretical Chemistry
Abstract
During the period of ARO support, we worked on four projects: (a) generalized Michaelis-Menten equation for enzymatic reactions; (b) counting statistics of single molecule reaction trajectories and single cell microarray data (c) analysis of cytoadhesion and binding kinetics experiments; and (d) optimization of coherent energy transfer in photosynthetic light-harvesting systems. The results are summarized in several publications and manuscripts. These research projects are motivated by single molecule measurements of complex biophysical processes, including photosynthetic energy transfer, enzymatic turnover reactions, and adhesion of cells. Single molecule experiments probe stochastic fluctuations on a broad range of temporal and spatial scales and therefore require detailed dynamic modeling and data analysis to extract useful molecular-level information. The sponsored research projects converge to a unified approach of correlating non-linear measurements with physical properties of complex systems.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 26, 2015
- Accession Number
- ADA623722
Entities
People
- Jianshu Cao
- Robert Silbey
Organizations
- Massachusetts Institute of Technology