Complement and Immunoregulation in Tissue Injury

Abstract

Our goal is to ultimately enable the development of novel therapeutic agents and strategies to ameliorate tissue injury in I/R related conditions. Preliminary findings suggested a role for Il-17 & IL-23 axis in ischemia reperfusion injury which we have continued to study. We have shown that by depleting IL-17 and IL-23 tissue injury is alleviated.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2014
Accession Number
ADA624271

Entities

People

  • George Tsokos

Organizations

  • Beth Israel Deaconess Medical Center

Tags

DTIC Thesaurus Topics

  • Antibodies
  • B Lymphocytes
  • Blood
  • Blood Cells
  • Cardiovascular System
  • Cells
  • Endothelial Cells
  • Epithelial Cells
  • Hematopoietic Cells
  • Intercellular Junctions
  • Intestines
  • Ischemia
  • Lymphocytes
  • Molecules
  • Small Intestine
  • Tissues
  • Vascular Diseases

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology and Pathology