The Prostate Cancer Biorepository Network (PCBN)

Abstract

The Genitourinary Cancer Biorepository at the University of Washington joined the Prostate Cancer Pathology Resource Network (PCBN) September 30th 2014. The purpose of this interaction is to provide high quality, well annotated specimens that can be used by prostate cancer researchers through the PCBN. The University of Washington Biorepository has a focus on advanced stage disease. Specimens provided by the University of Washington site includes blood (serum, plasma, and buffy coat), prostatectomy tissues (frozen), biopsies and metastatic tissue from rapid autopsies (paraffin embedded material and tissue microarrays (TMAs)), prostate cancer patient derived xenografts (PDX) and derived specimens (DNA and RNA) from prostate cancer patients. These specimens are linked to clinical and outcome data and supported by an informatics infrastructure. In this 1st year of operation the University of Washington Site has accrued new specimens from the clinic, surgery, and at autopsy, developed new PDX models, manufactured and provided TMAs, and derived RNA and DNA where required. In addition, we have provided material to conduct biospecimen science research in collaboration with the Johns Hopkins University site and specimens were made available to prostate cancer researchers through the PCBN.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
ADA624624

Entities

People

  • Colm Morrissey

Organizations

  • University of Washington

Tags

DTIC Thesaurus Topics

  • Acquisition
  • African Americans
  • Alkanes
  • Biomedical Research
  • Biorepositories
  • Cancer
  • Department Of Defense
  • Diseases And Disorders
  • Infrastructure
  • Materials
  • Medical Personnel
  • Neoplasms
  • Physicians
  • Prostate
  • Prostate Cancer
  • Tissues
  • Xenografts

Fields of Study

  • Biology

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Research Science/Academic Research