Layer-by-Layer Bioprinting of Stem Cells for Retinal Tissue Regeneration

Abstract

We aim to investigate a Layer-by-Layer (LBL) bioprinting process using stem cells for retinal tissue regeneration. The LBL nature of the bioprinting process matches nicely with the native, multilaminar anatomy of the retina. This research will bioprint retinal stem cells (RSCs) and appropriate growth factors (GF) encapsulated in a biomaterial (e.g. hyaluronic acid, HA). We will investigate the mechanical, chemical and biological properties of the hydrogel materials. We will study the cell viability and analyze the biological functions of the 3D printed retina tissue.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
ADA625958

Entities

People

  • Kang Zhang
  • Shaochen Chen

Organizations

  • University of California, San Diego

Tags

DTIC Thesaurus Topics

  • Additive Manufacturing
  • Bioengineering
  • Biomaterials
  • Bioprinting
  • Cells
  • Engineering
  • Fabrication
  • Femtosecond Lasers
  • Growth Factors
  • Materials
  • Medical Personnel
  • Membranes
  • Modulus Of Elasticity
  • Stem Cells
  • Students
  • Three Dimensional
  • Tissue Engineering

Fields of Study

  • Biology

Readers

  • Nanocomposite Materials Science
  • Neurotrauma and Rehabilitation Medicine.
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology