Meditation for Depression: A Systematic Review of Mindfulness-Based Cognitive Therapy for Major Depressive Disorder
Abstract
Depression is a prevalent psychological health condition and clinical diagnoses such as major depressive disorder (MDD) are associated with significant burden in terms of reduced quality of life, lower productivity, increased prevalence of other conditions and increased health care costs. Several meditation approaches including mindfulness-based cognitive therapy (MBCT) have shown promise in the treatment of depression and the prevention of relapse. We conducted a systematic review of randomized controlled trials (RCTs) that assessed the efficacy and safety of MBCT for the treatment of patients diagnosed with MDD. We searched the databases PubMed, CINAHL, PsycINFO, Web of Science, Embase, CDSR, CENTRAL, DARE, clinicaltrials.gov, and PILOTS for English language RCTs published to January 2015. Two independent reviewers screened retrieved publications using a set of inclusion and exclusion criteria, abstracted study level data and assessed the quality of included studies. Meta-analysis was performed using the Hartung-Knapp-Sidik-Jonkman method for random-effects models. Quality of evidence was assessed using GRADE.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2015
- Accession Number
- ADA626456
Entities
People
- Christine Vaughan
- Coreen A. Farris
- Eric Apaydin
- Jennifer Sloan
- Jeremy Miles
- Kerry A. Reynolds
- Melony E. Sorbero
- Ryan Kandrack
- Sangeeta Ahluwalia
- Susan L. Lovejoy
Organizations
- RAND Corporation