Discovery of FDA-Approved Drugs that Promote Retinal Cell Survival or Regeneration
Abstract
Ocular trauma due to blast or blunt forces affect millions of people worldwide, which often result in an irreversible loss of visual function. However, therapeutic approaches that can reverse this process or promote protection are limited. Recently, research on the damaged zebrafish retina has highlighted the potential of the Muller glia (MG) cells to function as a retinal stem cell to regenerate lost neurons. It is now appreciated that MG cells may retain the potential for retinal repair across vertebrate species, including humans.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2015
- Accession Number
- ADA626588
Entities
People
- Donald Zack
- Harry Quigley
- Jeffrey Mumm
- Justin Hanes
Organizations
- Johns Hopkins University