Molecular & Genetic Investigation of Tau in Chronic Traumatic Encephalopathy

Abstract

Repetitive mild TBI leads to chronic traumatic encephalopathy (CTE), but the underlying molecular changes remain unclear. Here, biochemical and genetic studies that deepen our understanding of the pathogenesis of CTE will be performed, facilitating diagnosis and therapeutic development. This award has been in the transfer process from Columbia University to the Icahn School of Medicine at Mount Sinai until 10/28/2015, thus no funds have been available to initiate the project. Now that funds are available, work will commence.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
ADA626598

Entities

People

  • John F. Crary

Organizations

  • Icahn School of Medicine at Mount Sinai

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Alzheimer Disease
  • Biomedical Research
  • Brain Injuries
  • Chronic Encephalopathy
  • Department Of Defense
  • Diseases And Disorders
  • Governments
  • Information Operations
  • National Governments
  • New York
  • Schools
  • Universities

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.

Technology Areas

  • Biotechnology