A New Therapeutic Paradigm for Breast Cancer Exploiting Low Dose Estrogen-Induced Apoptosis
Abstract
The purpose of the CoE is to discover the molecular mechanisms and the modulation of estrogen-induced apoptosis. The laboratory research project is focused on genomics nad proteomics with a current focus on molecular interrogation to decipher mechanisms that may be applied to aid patient treatment. In parallel, but not supported by the CoE, is a pilot clinical study of estrogen-induced apoptosis in patients with metastatic breast cancer, that have had repeated cycles of successful antihormone therapy, but have subsequently failed and relapsed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 2012
- Accession Number
- ADA627935
Entities
People
- Virgil C. Jordan
Organizations
- Georgetown University