Restoration of Central Blood Volume: Application of a Simple Concept and a Simple Device to Counteract Cardiovascular Instability in Syncope and Hemorrhage
Abstract
The inability to tolerate upright standing posture due to development of severe orthostatic hypotension and syncope is a clinical problem that has plagued astronauts and military personnel in their austere operational environments as well as millions of people worldwide. More critically, hemorrhagic shock remains a leading cause of death in both civilian and battlefield trauma. Central hypovolemia and cardiovascular collapse (insufficiency) are the common features shared by syncope and hemorrhagic shock. It is therefore clear that the development of an effective countermeasure against the onset of syncope or hemorrhagic shock should focus on the simple concept of functionally restoring central blood volume. Although replacing blood or fluids may be beneficial in a clinical setting, it can prove impossible in operational settings such as a spacecraft and battlefields.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2005
- Accession Number
- ADA628188
Entities
People
- Keith G. Lurie
- Victor A Convertino
- William H. Cooke
Organizations
- United States Army Institute of Surgical Research