Methods for Improved Hemorrhage Control

Abstract

Trauma is the leading cause of death from age 1 to 34 years and is the fifth leading cause of death overall in the USA, with uncontrolled hemorrhage being the leading cause of potentially preventable death. Improving our ability to control hemorrhage may represent the next major hurdle in reducing trauma mortality. New techniques, devices, and drugs for hemorrhage control are being developed and applied across the continuum of trauma care: prehospital, emergency room, and operative and postoperative critical care. This brief review focuses on drugs directed at life-threatening hemorrhage. The most important of these new drugs are injectable hemostatics, fibrin foams, and dressings. The available animal studies are encouraging and human studies are required.

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Document Details

Document Type
Technical Report
Publication Date
Jun 14, 2004
Accession Number
ADA628237

Entities

People

  • John B Holcomb

Organizations

  • United States Army Institute of Surgical Research

Tags

DTIC Thesaurus Topics

  • Blood
  • Bone Fractures
  • Cardiovascular Physiological Phenomena
  • Cardiovascular Surgery
  • Health Services
  • Hemorrhage
  • Hospitals
  • Medical Personnel
  • Patient Care
  • Shock (Pathology)
  • Therapy
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Trauma Surgery or Emergency Medicine.
  • Trauma or Military Medicine