Evidence for Central Venous Pressure Resetting During Initial Exposure to Microgravity

Abstract

We measured central venous pressure (CVP); plasma volume (PV); urine volume rate (UVR); renal excretion of sodium (UNa); and renal clearances of creatinine, sodium, and osmolality before and after acute volume infusion to test the hypothesis that exposure to microgravity causes resetting of the CVP operating point. Six rhesus monkeys underwent two experimental conditions in a cross- over counterbalance design: 1) continuous exposure to 10 head-down tilt (HDT) and 2) a control, defined as 16 h/day of 80 Degrees head-up tilt and 8 h prone.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2001
Accession Number
ADA628358

Entities

People

  • Charles E Wade
  • David A. Ludwig
  • James J. Elliott
  • Victor A Convertino

Organizations

  • United States Army Institute of Surgical Research

Tags

DTIC Thesaurus Topics

  • Animals
  • Blood
  • Blood Volume
  • Cardiovascular Physiological Phenomena
  • Catheterization
  • Catheters
  • Central Nervous System
  • Fluids
  • Ground Based
  • Heart Rate
  • Laboratory Animals
  • Measurement
  • Nervous System
  • North Carolina
  • Rhesus Monkeys
  • Sedation
  • Urinary Tract Physiological Phenomena

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology