Negative Pressure Wound Therapy Reduces Pseudomonas Wound Contamination More Than Staphylococcus Aureus
Abstract
Purpose: The purpose of this study is to determine if negative pressure wound therapy (NPWT) treatment results in fewer bacteria than wet-to-dry (WTD) dressings in a contaminated open fracture wound model. Methods: For Study 1, complex wounds were created on the proximal left leg of goats. The wounds were inoculated with Pseudomonas aeruginosa. The wounds were de brided and irrigated 6 hours after inoculation. The first group received WTD dressing changes twice daily; the second and third groups received NPWT using systems from two different companies. All three groups received repeat de bridements every 48 hours for 6 days. Bacteria quantification was performed both immediately before and after each de bridement. For Study 2, the only changes were that Staphylococcus aureus was used and only one NPWT group was included.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 2010
- Accession Number
- ADA628714
Entities
People
- Brendan D. Masini
- Daniel J. Stinner
- Joanna G. Branstetter
- Joseph C Wenke
- Scott M. Waterman
- Steven J. Lalliss
Organizations
- United States Army Institute of Surgical Research