Association of Shock, Coagulopathy, and Initial Vital Signs with Massive Transfusion in Combat Casualties

Abstract

Background: Timely initiation of a massive transfusion (MT) protocol is associated with improved survival and reduced transfusion for patients requiring MT; however, a priori identification of this population is difficult. The objective of this study was to compare the results of an MT prediction model and actual MT incidence in combat casualties. Methods: We performed a retrospective review of the Joint Theater Trauma Registry transfusion database for all US service personnel injured in combat during overseas contingency operations who received at least 1 unit of blood. Systolic blood pressure at the time of admission, heart rate, hemoglobin, international normalized ratio, and base deficit were used in a previously developed prediction model for MT.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2010
Accession Number
ADA628729

Entities

People

  • Charles E Wade
  • Christopher E. White
  • Claire R. Larson
  • John A. Jones
  • John B Holcomb
  • Lorne H Blackbourne
  • Philip C Spinella

Organizations

  • United States Army Institute of Surgical Research

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Transfusions
  • Cardiovascular Physiological Phenomena
  • Casualties
  • Databases
  • Head Injuries
  • Health Services
  • Heart Rate
  • Hemorrhage
  • Medical Personnel
  • Patient Care
  • Physical Examination (Medicine)
  • Physicians
  • Predictive Modeling
  • United States
  • Vital Signs
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Computational Modeling and Simulation
  • Trauma or Military Medicine