Dynamic Changes in Shunt and Ventilation-Perfusion Mismatch Following Experimental Pulmonary Contusion

Abstract

ACT The objective of this study was to investigate early changes in oxygenation by means of the multiple inert gas elimination technique and in coagulation by means of thromboelastography (TEG) after right-sided pulmonary contusion (PC) in swine. Anesthetized swine (group 1; n 8) sustained a right-chest PC by a captive-bolt stunner. Multiple inert gas elimination technique, TEG, and thoracic computed tomography (CT) scans were performed before and 10, 30, 60, and 120 min after injury. Three-dimensional CT scan reconstruction enabled measurement of volumes of poorly (VolPoor) and nonaerated (VolNon) lung.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2010
Accession Number
ADA629375

Entities

People

  • Andriy I Batchinsky
  • Bryan S. Jordan
  • Corina Necsoiu
  • Leopoldo C. Cancio
  • Michael A. Dubick

Organizations

  • United States Army Institute of Surgical Research

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Arteries
  • Blood
  • Blood Flow
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Health Services
  • Hemorrhage
  • Hemorrhagic Shock
  • Lung Diseases
  • Measurement
  • Rate Of Formation
  • Resuscitation
  • Thoracic Injuries
  • Three Dimensional
  • Veins
  • Wounds And Injuries
  • X-Ray Computed Tomography

Readers

  • Cardiovascular Physiology
  • Combustion Dynamics and Shock Wave Physics.
  • Medical Imaging.