Oxidative Stress Precedes Circulatory Failure Induced by 35-GHz Microwave Heating

Abstract

Sustained whole-body exposure of anesthetized rats to 35-GHz radio frequency radiation produces localized hyperthermia and hypotension, leading to circulatory failure and death. The physiological mechanism underlying the induction of circulatory failure by 35-GHz microwave (MW) heating is currently unknown. We hypothesized that oxidative stress may play a role in the pathophysiology of MW-induced circulatory failure and examined this question by probing organs for 3-nitrotyrosine (3/NT), a marker of oxidative stress.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2000
Accession Number
ADA630520

Entities

People

  • John G Bruno
  • John Kalns
  • Jonathan L. Kiel
  • Kathy L. Ryan
  • Patrick A. Mason
  • Robert Gooden

Organizations

  • United States Army Institute of Surgical Research

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Blood Cells
  • Blood Proteins
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Electromagnetic Radiation
  • Free Radicals
  • Frequency
  • Health Services
  • Heart Rate
  • Hemorrhagic Shock
  • Leukocytes
  • Oxidative Stress
  • Proteins
  • Radiation
  • Radio Frequency
  • Surgery

Readers

  • Cardiovascular Physiology
  • Electronics Engineering
  • Pulsed Power and Plasma Physics.