Challenge of N95 and P100 Filtering Facepiece Respirators with Particles Containing Viable H1N1

Abstract

3M1860s (N95) and 3M 8293 (P100) NIOSH-approved filtering facepiece respirators (FFRs) were challenged with aerosolized particles of H1N1 influenza to measure the amount of viable influenza virus that penetrates each device. The test was conducted at the NIOSH-recommended flowrate of 85 LPM using guidance provided by a Department of Defense test standard developed for challenging air purification devices with viable microbial aerosols. The count mode diameter (CMD) particle size of the challenge aerosol was approximate 0.8 microns, which was created by aerosolizing H1N1 influenza virus in an artificial saliva buffer using the Laboratory-Scale Aerosol Tunnel (LSAT). In addition to the H1N1 challenge, each FFR was also challenged with 0.8- microns inert beads. In these tests the N95 FFR (n = 3) removed > 99% of the viable H1N1 from the air stream and the P100 (n =3) removed > 99.99% of viable H1N1 from the airstream. The percent reductions in mechanical and viable particle counts measured for each FFR using the 0.8- microns bead challenge were equivalent to the percent reduction values measured for like-sized particles containing H1N1, verifying that bioaerosols act as typical particles. These data demonstrate that the N95 and P100 FFR will reduce viable H1N1 aerosol from the airstream at greater than or equal to their rated value.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Dec 02, 2009
Accession Number
ADA631314

Entities

People

  • Brian Heimbuch
  • Joseph D. Wander

Organizations

  • Applied Research Associates (United States)

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Biological Aerosols
  • Culture Techniques
  • Data Analysis
  • Dental Materials
  • Department Of Defense
  • Flow Rate
  • Governments
  • Health Services
  • Materials
  • Measurement
  • Particle Size
  • Statistical Analysis
  • Test Methods
  • United States
  • Viruses

Readers

  • Aerosol Science/Aerosol Physics
  • Agricultural Chemistry/Soil Science
  • Military/Explosive Ordnance Disposal (EOD) Technology

Technology Areas

  • Biotechnology