Severe Controlled Hemorrhage Resuscitation with Small Volume Poloxamer 188 in Sedated Miniature Swine

Abstract

Background: The surfactant polxamer 188 (P188) has been shown to improve survival following hemorrhage. This study used P188 as a small volume resuscitation product in sedated, sexually mature, male miniature swine severe hemorrhage model for potential improvement in rate and time of survival.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2011
Accession Number
ADA633031

Entities

People

  • Charles E Wade
  • John A. Jones
  • John W. Burns
  • Lisa A. Baer
  • Michael A. Dubick

Organizations

  • United States Army Institute of Surgical Research

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Arteries
  • Blood
  • Blood Chemistry
  • Blood Coagulation
  • Blood Coagulation Factors
  • Blood Flow
  • Cardiovascular Physiological Phenomena
  • Chemistry
  • Data Science
  • Hemorrhage
  • Hemorrhagic Shock
  • Medical Personnel
  • Military Operations
  • Resuscitation
  • Veins

Fields of Study

  • Chemistry
  • Medicine

Readers

  • Trauma Surgery or Emergency Medicine.