Identification of the srtC1 Transcription Start Site and Catalytically Essential Residues Required for Actinomyces oris T14V SrtC1 Activity

Abstract

In Actinomyces oris T14V, sortase SrtC1 mediates the assembly of type 1 fimbriae. We analyzed the effects of the conserved residues (H184, H204, F213, Y236, L263, T265, C266 and R275) on the SrtC1 activity by site directed mutagenesis.

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Document Details

Document Type
Technical Report
Publication Date
Jul 27, 2011
Accession Number
ADA633554

Entities

People

  • Kai Poon Leung
  • Ping Chen

Organizations

  • United States Army Institute of Surgical Research

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Actinobacteria
  • Amino Acids
  • Anti-Bacterial Agents
  • Bacteria
  • Bacteriology
  • Cells
  • Cellular Structures
  • Chemistry
  • Crystal Structure
  • Escherichia Coli
  • Essential Amino Acids
  • Governments
  • Identification
  • Microbiology
  • Microbiomes
  • Staphylococcus Aureus
  • Streptococcus

Readers

  • Data Mining and Knowledge Discovery.
  • Microbial Pathology
  • Molecular Genetics