The Role of Pituitary Beta-Endorphin in the Attenuation of Nociception
Abstract
This research project examined the relationship between pituitary beta-endorphin (B-END) levels and pain in both humans and animals. The clinical trials examined this relationship through pharmacological interventions, both stimulatory and inhibitory, on release of pituitary B-END in patients prior to the onset of acute post-operative pain. Experiments using laboratory animals further investigated this relationship through interventions of both endocrine and opiate activity.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 28, 1986
- Accession Number
- ADA634084
Entities
People
- Kenneth M Hargreaves
Organizations
- Uniformed Services University of the Health Sciences