Antigen Transport.

Abstract

Antiserum to nuclei, microsomes, mitochondria and lysosomes was prepared. The antisera were in an allograft system. Only the lysosomal antiserum was found to suppress the allograft response. Protein transport in macrophages was studied. Denaturation and the degree of iodination was found to influence protein transport. A series of antigens were tested for immunogenicity. The same antigens were subjected to hydrolysis by cathepsins. The most immunogenic of the antigens were not hydrolyzed by the cathepsins and the least immunogenic were hydrolyzed extensively.

Document Details

Document Type
Technical Report
Publication Date
Feb 08, 1971
Accession Number
ADA955163

Entities

People

  • Wayne L. Ryan

Organizations

  • University of Nebraska Omaha

Tags

DTIC Thesaurus Topics

  • Allografts
  • Anatomy
  • Antigens
  • Biological Factors
  • Biological Sciences
  • Cells (Biology)
  • Cellular Structures
  • Hydrolysis
  • Immune Serums
  • Immunogenicity
  • Iodination
  • Lysosomes
  • Macrophages
  • Microsomes
  • Proteins
  • Transport Ships

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Molecular and Cellular Biochemistry