Research on Immunopathology of Malaria and Other Hemosporidian Infections.

Abstract

We, as have others, have noted that P. chabaudi infection is contaminated with E. coccoides and that in mice this infection becomes very prominent as P. chabaudi parasitemia develops. We have isolated this E. coccoides and we find it produces a high parasitemia with moderate to severe anemia in mice 3-5 days after infection. All mice have usually recovered from parasitemia and anemia within 2-3 weeks after infection. We have tested the sera of mice that have recovered from E. coccoides infection in the TBF test using serum antigen of P. Iophurae duck origin. We invariably get positive reactions with titers varying from 1:20 - 1:320 with sera of our recovered mice and serum from our uninfected mice are usually negative. (jes)

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1967
Accession Number
ADA955935

Entities

People

  • Herbert W. Cox

Organizations

  • Michigan State University

Tags

DTIC Thesaurus Topics

  • Bacterial Infections And Mycoses
  • Infection
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Immunology
  • Parasitology and Pharmacology of Malaria.