Prevention of Influenza and other Respiratory Diseases

Abstract

This report summarizes a study of a population of about 9000 individuals at Lowry AFB. Illness rates due to the 1977 influenza A strains were low (about 5%) in unvaccinated young adults. Illness rates were considerably lower in persons who had received vaccine containing 400 CCA units of A/ victoria/3/75. Vaccine efficacy, by the lowest estimate, was 73%, and was probably considerably higher. The new influenza A strain, as represented by A/ denver/1/77 did not spread into the surrounding civilian community. Data currently available indicate that A/Victoria/75 vaccine provided a high level of protection, and that a change in vaccine composition is not necessary. A modest outbreak of influenza B occurred in the metropolitan Denver civilian community, and was reflected by a small number of cases of influenza B that occurred at Lowry AFB, primarily in permanent party personnel. A significant rubella outbreak occurred during January and February, 1977, among both male and female students at Lowry AFB. Despite outbreaks of influenza A and rubella, the incidence of febrile respiratory disease at Lowry AFB remain generally low. Adenovirus illness was virtually absent, and streptococcal pharyngitis occurred at only a low level. Investigations are continuing to define the reasons for the unexpected HI antibody response to PR8 antigen in sera of students who received A/New Jersey/76 vaccine.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1977
Accession Number
ADB024470

Entities

People

  • Gordon Meiklejohn
  • Theodore C. Eickhoff

Organizations

  • University of Colorado Boulder

Tags

DTIC Thesaurus Topics

  • Adenoviruses
  • Air Force
  • Air Force Facilities
  • Air Force Personnel
  • Antibodies
  • Biomedical Research
  • Classification
  • Communities
  • Diseases And Disorders
  • Health Services
  • Medical Personnel
  • New Jersey
  • Respiratory Tract Diseases
  • Students
  • United States
  • Vaccines
  • Viruses

Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Mathematics or Statistics

Technology Areas

  • Biotechnology