The Acute Effects of Single Exposures to White Phosphorus Smoke in Rats and Guinea Pigs

Abstract

Toxicity studies were conducted to determine the acute effects of single exposures to a white phosphorus screening smoke. Results indicate that the smoke is moderately toxic in rats (16% mortality at Ct of 62,200 mg min/cu m; 99% mortality at Ct of 248,250 mg min/cu m) and highly toxic in guinea pigs (16% mortality at Ct of 4600 mg min/cu m; 99% mortality at Ct of 7439 mg min/cu m). Surviving animals appear fully recovered 2 weeks after exposure, based on appearance, blood chemistries, lung function tests, and pathology.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1980
Accession Number
ADB051836

Entities

People

  • Bernard J. Brown
  • Dale H. Heitkamp
  • Fred K. Lee
  • Garnet E. Affleck
  • Richard L. Farrand

Organizations

  • United States Army Armament Research, Development and Engineering Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acids
  • Blood
  • Blood Chemistry
  • Cells
  • Chemical Analysis
  • Chemical Synthesis
  • Chemistry
  • Chromosomes
  • Diptera
  • Drosophila
  • Health Services
  • Phosphoric Acids
  • Plastic Explosives
  • Rodents
  • Statistical Analysis
  • Test And Evaluation
  • United States Government

Fields of Study

  • Medicine

Readers

  • Toxicology/Environmental Toxicology