Investigations Concerning Hydrolysis and Stabilization of Antiradiation Compounds

Abstract

This report contains results of the following studies: Encapsulation of ethiofos for use as oral dosage forms; In vitro evaluation of the most promising samples; Development of analytical methodology for ethiofos, WR-1065, WR-33278 and Pharmacokinetic results of in vivo studies. (Keywords: Antiradiation compounds: ethiofos, WR-2721, WR-1065, WR-33278, hydrolytic and thermal properties, encapsulation, drug dosage forms, blood plasma assay, pharmacokinetics.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1985
Accession Number
ADB109071

Entities

People

  • C. W. Lew
  • D. J. Mangold
  • E. P. Mcgovern
  • N. F. Swynnerton
  • T. M. Ludden

Organizations

  • Southwest Research Institute

Tags

DTIC Thesaurus Topics

  • Accuracy
  • Alcohols
  • Blood
  • Blood Volume
  • Buffers (Chemistry)
  • Chemistry
  • Detectors
  • Dosage Forms
  • Electrochemical Cells
  • Encapsulation
  • Ionizing Radiation
  • Laboratory Animals
  • Liquid Chromatography
  • Measurement
  • Medical Personnel
  • Microcapsules
  • Veins

Fields of Study

  • Education
  • Medicine

Readers

  • Polymer Science and Engineering.
  • Toxicology/Environmental Toxicology