Design and Synthesis of Candidate Prophylactic and Therapeutic Compounds for use in the Management of Organophosphorus Poisoning.
Abstract
The program is directed at the design and synthesis of new compounds for use in the management of organophosphorus poisoning. In the past three years, 48 compounds were submitted: 26 organophosphinates, one organophosphinothioate, 2 organophosphonates, 2 organophosphates, one oxophospholane, 7 carbamates, 2 sugar oximes, 2 aminoalkylselenic and selonic acids and five other organic compounds. Keywords: Organophosphates; Carbamates; Prophylactics; Therapeutics; Antidotes.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1986
- Accession Number
- ADB111422
Entities
People
- C. L. Stevens
- J. P. Pease
- M. A. Priest
- P. Blumbergs
- P. L. Knutson