Chemotherapy of Rodent Malaria. Part 1

Abstract

The main emphasis of work has been on our continuing studies into drug resistance, involving further examinations of cross-resistance patterns in resistant lines. In addition, ultrastructural studies comparing treated and untreated parasites resistant to a wide range of antimalarials have been carried out. Some preliminary studies into the in vivo effect of calcium channel blockers on chloroquine resistant strains of rodent malaria have also been undertaken. A problem which was encountered with a virus infection in our mosquito colony stimulated a series of studies into the action of some antiviral agents on polyhedrosis virus in Anopheles stephensi. Ultrastructural studies of treated and control mosquitoes are included in this report. Keywords: Chemotherapy.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1987
Accession Number
ADB121870

Entities

People

  • Wallace Peters

Organizations

  • London School of Hygiene & Tropical Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Antimalarials
  • Antiviral Agents
  • Cells
  • Cellular Structures
  • Chemical Synthesis
  • Chemistry
  • Chemotherapy
  • Cytoplasm
  • Electron Microscopes
  • Electron Microscopy
  • Endoplasmic Reticulum
  • Infection
  • Infectious Diseases
  • Intracellular Membranes
  • Malaria
  • Organelles

Fields of Study

  • Medicine

Readers

  • Parasitology and Pharmacology of Malaria.
  • Systems Analysis and Design