MULTIPLE ANIMAL STUDIES FOR MEDICAL CHEMICAL DEFENSE PROGRAM IN SOLDIER/PATIENT DECONTAMINATION AND DRUG DEVELOPMENT. TASK 85-01. OPTIMIZATION OF TEST AND RESPONSE CONDITIONS IN A PROTOCOL TO COMPARE THE EFFECTIVENESS OF EXPERIMENTAL DECONTAMINATION SYSTEMS WITH THE M258A1 KIT AGAINST PERCUTANEOUS APPLICATION OF UNDILUTED VESICANT CHEMICAL SURETY MATERIEL TO LABORATORY ALBINO RABBIT
Abstract
A task was assigned to optimize a screening protocol to compare candidate decontamination systems with dual-component standard system (M258A1) currently fielded to determine the best conditions for experimentation and response expression in decontaminating rabbits exposed percutaneously to sulfur mustard (HD) or Lewisite (L). Five different procedures were evaluated including improved statistics and different methods of lesion evaluation. Keywords: Decontamination, Rabbits, Vesicants, M258A1 Kit, Screen, Mustard agents.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1988
- Accession Number
- ADB124424
Entities
People
- H. H. Harroff Jr.
- Paul I. Feder
- Ronald L. Joiner
- Thomas H. Snider
- W. B. Keys Jr.
Organizations
- Battelle Memorial Institute