Determination of the In Vitro and In Vivo Activity of Compounds Tested Against Punta Toro Virus

Abstract

Partial Contents: In Vivo Assessment of Toxicity; In Vitro Evaluation of Test Compounds Against Adames Strain and Balliet Strain Punta Toro Virus; In Vivo Anti-Punta Toro Virus Activity of AVS Compounds; Effect of AVS Compounds on Hepatotropic Infections and Intracerebral Infections in Mice; Effect of a Combination of AVS01 and AVS206 on In Vitro Punta Toro Virus Infections; Effect of the combination of AVS206 and AVS2776 on In Vivo Punta Toro Virus Infections; Effect of the Combination of AVS01 and AVS1754 on In Vivo Punta Toro Virus Infections; Effect of a Combination of AVS206 and AVS1767 on In Vivo Punta Toro Virus Infections; Effects on Treatment with AVS206 on Delayed Infection Parameters in Punta Toro Virus-Infected Mice; Infectivity of Balliet Strain PTV; Effect of intravenous Therapy on Intracerebrally Induced Punta Toro Virus infections; Induction of Lethal Disease in Mice Using Intranasal Administration of Balliet Strain Punta Toro Virus; Punta Toro Virus-Induced Hematologic Effects in C57BL/6 Mice; Effects of Various Metabolic Precursors on the Anti-Punta Toro Virus Activity of AVS206; Effects of AVS01 and AVS206 on Uptake of Radiolabeled Metabolic Precursors as a Measure of Cytotoxicity; Interferon Induction by AVS2776; In Vitro Antiviral Activity of Immunomodulators.

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Document Details

Document Type
Technical Report
Publication Date
Dec 20, 1988
Accession Number
ADB134374

Entities

People

  • Robert W. Sidwell

Organizations

  • Utah State University

Tags

DTIC Thesaurus Topics

  • Anti-Infective Agents
  • Antiviral Agents
  • Blood
  • Blood Cells
  • Body Weight
  • Cells
  • Ceramic Matrix Composites
  • Chemistry
  • Chemotherapy
  • Infection
  • Interferon
  • Leukocytes
  • Lymphocytes
  • Macrophages
  • Medical Personnel
  • Plastic Explosives
  • Viruses

Fields of Study

  • Biology

Readers

  • Toxicology/Environmental Toxicology
  • Virology (or Medical Virology).