Research and Preparation of an Equine Heptavalent Botulinal Antitoxin
Abstract
The following report describes the immunization and proprietary plasmapheresis methods used to produce equine hyperimmune botulinal antitoxin plasma. Also included are proprietary methods used for large scale production of an equine botulinal antitoxin with the highest specific neutralizing activity, the lowest potential for sensitization, and consisting of over 95% equine (F(ab')2 immunoglobulin. Finally, this report describes the proprietary large scale production and testing of two preparations of equine heptavalent botulinal antitoxin, FFA1-3-45-4x1 and FFA2-3-45-4xl. Keywords: RAI; New heptavalent F(ab')2 botulinal antitoxin equine; Toxin; Immunology; Antitoxin; Neurotoxin; Toxicology.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1989
- Accession Number
- ADB141387
Entities
People
- Richard M. Condie
Organizations
- University of Minnesota