Development of a Toxin Knowledge System
Abstract
The development of a Toxin Knowledge System (TKS) was begun in an attempt to meet the needs for readily accessible toxin knowledge. This system was designed to extract facts from published literature using structured abstracting techniques, store these facts in a standard knowledge structure, control the terminology entered through the use of a standard nomenclature system, and subsequently generate standard monographs on individual toxins. The system uses a relational database management system and associated programming language on a microcomputer. Standard nomenclature systems were created for clinical findings, journal abbreviations, study terminology, and book information. The development of a chemical vocabulary was unsuccessful. The current TKS version is of primary value with papers describing in vivo toxicology studies. The TKS application facilitates the extraction of needed information from both journals and books through a sophisticated user interface. The user enters citation data and is then prompted for information about each study design (up to 99 per paper), each subject group (up to 99 per design) and exposure regimen (up to 99 per design) within each design, and how these factors interact to produce clinical effects.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 12, 1990
- Accession Number
- ADB152646
Entities
People
- Harold L. Trammel
Organizations
- University of Illinois Urbana–Champaign