Synthesis Laboratory for the U.S. Army Medical Research Institute of Infectious Diseases Selection Panel

Abstract

A synthesis laboratory has been established for the preparation of compounds to be evaluated against viruses of interest of U.S. Army Medical Research Institute of Infectious Diseases. The synthesis of known compounds as well as new compounds has been undertaken, and all compounds are being made in sufficient quantity to allow for full evaluation. Among the compounds prepared thus far are 1-benzyloxy-adenosines, 9-substituted 1-benzyloxyadenines, 1,2,4,5,3,6,-tetraazadiphosphorines, substituted imidazoles, selenadiazoles, triazoles, triazolotriazoles, guanidines, pyrazoles, adamantane derivatives, chloroquines, Ni-aminonucleosides, allopurinol acyclonucleosides, nucleotides of ribavirin and tiazofurin, and various other heterocyclic compounds.

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Document Details

Document Type
Technical Report
Publication Date
Jun 26, 1991
Accession Number
ADB157566

Entities

People

  • Cecil D. Kwong
  • Charles A. Krauth
  • Deborah A. Carter
  • George S. Mccaleb
  • John Iii A. Secrist
  • Lisa K. Hanna

Organizations

  • Southern Research

Tags

Communities of Interest

  • Biomedical
  • C4I

DTIC Thesaurus Topics

  • Chemical Synthesis
  • Chemistry
  • Dermatologic Agents
  • Fungi
  • Organic Chemistry

Fields of Study

  • Chemistry

Readers

  • Parasitology and Pharmacology of Malaria.