Epidemiologic Investigation of a Cluster of Cystosarcoma Phyllode Tumors of the Female Breast

Abstract

Cystosarcoma phyllodes is an uncommon breast neoplasm. It is a fibroepithelial tumor composed of an epithelial and a cellular stromal component. A significant number of cases of cystosarcoma phyllodes tumors were diagnosed over the last several years at a single hospital in New Jersey. This study is systematically assessing the epidemiology of this tumor. Initial results confirm an apparent excess of cases compared to the number expected, with a total of 97 women diagnosed with new tumors since 1987. However, the incidence of cystosarcoma phyllodes does not appear to be increased in neighboring counties. Benign cystosarcoma phyllodes tumors were found to have a significant risk of recurrence unless there are adequate surgical margins. An analytic epidemiologic case-control study will assess possible risk factors and provide guidance to future study.

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Document Details

Document Type
Technical Report
Publication Date
Sep 14, 1995
Accession Number
ADB215483

Entities

People

  • Stanley H. Weiss

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Availability
  • Biomedical Research
  • Breast Cancer
  • Cancer
  • Genetics
  • Health Services
  • Hospitals
  • Materials
  • Medical Personnel
  • Neoplasms
  • New Jersey
  • Physicians
  • Risk Factors
  • Sarcoma
  • United States

Fields of Study

  • Medicine

Readers

  • Emergency Management and Homeland Security.
  • Molecular and genetic basis of cancer.
  • Oncology and Biomarker-Based Cancer Detection.