Development of a Cold Sterilant for Field Medical Use.
Abstract
A peracid sterilant formulation was developed to the Army's performance requirements for a powdered cold sterilant for field use as a replacement for glutaraldehyde. The active biocidal agent, peracetic acid, is generated in situ and the working life may be up to eight hours with reuse at 20 deg C. AOAC carrier testing showed the formulation to be sporicidal within 20 minutes at its minimum effective concentration. The objectives for Phase II were to: (1) select through further testing one of two sterilant formulations developed through Phase I, (2) develop packaging for the selected sterilant to assure safe and efficient transportation and storage, (3) further demonstrate sterilant safety and efficacy by obtaining EPA regulatory approval and FDA clearance to market and (4) deliver to USAMRMC prototype packaged sterilants (with appropriate labeling and use instructions and biological and chemical indicators) to permit the USAMRMC to conduct initial field tests following completion of Phase II.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1996
- Accession Number
- ADB218773
Entities
People
- Paul S. Malchesky