The Molecular Epidemiology of Breast Cancer: Risk from Environmental Exposures and Genetic Susceptibility.

Abstract

This work is a continuation of the effort to determine environmental and genetic determinants of breast cancer. Since the last report data on serum organochlorine levels, e.g. serum DDE, HCB, total PCBs, and mirex, became available. These data were explored by first conducting a thorough descriptive analysis. Results from this cross-sectional research suggested that increased fruit and vegetable intake may be associated with higher levels of serum DDE, HCB, and total PCBs. No associations with fish intake were observed for any of the compounds under investigation. Weak associations were found for intake of individual meats and dairy products and serum levels of DDE, HCB, and total PCBs. Caffeine intake appeared to be inversely related to DDE, HCB, and total PCBs. We observed no strong inverse associations with any of these compounds and duration of lactation. Future analytic efforts will focus on the association between these organochlorine compounds and breast cancer risk.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1996
Accession Number
ADB219519

Entities

People

  • Kirsten Moysich

Organizations

  • University at Buffalo

Tags

DTIC Thesaurus Topics

  • Adipose Tissue
  • Alkanes
  • Animals
  • Cancer
  • Chemistry
  • Environmental Health
  • Epidemiology
  • Fish
  • Geographic Regions
  • Health
  • Health Services
  • New York
  • Physical Activity
  • Polychlorinated Biphenyls
  • Public Health
  • Regression Analysis
  • Toxicology

Readers

  • Aquatic Ecology
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology
  • Biotechnology - Bioremediation