Developing New Epidemiologic Tools for Investigating Breast Cancer Risk

Abstract

The overall aim of this project is to develop new biological markers that can improve epidemiological investigations into the etiology of breast cancer. Our studies encompass three types of novel biomarkers: (a) breast fluid from nipple aspirates for measurement of growth factors and steroids, (b) saliva for measurement of sex steroid concentrations, and (c) normal breast tissue from biopsy samples for assessment of lobular differentiation. These biomarkers will allow epidemiologists to study the development of breast cancer in greater biological detail than previously possible using conventional questionnaire-based research. To allow consistency with our previous reports, we will refer to all activities related to hormone or growth factor levels as Project 1; activities related to lobular differentiation will be referred to as Project 2

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1996
Accession Number
ADB221482

Entities

People

  • Peter H Gann

Organizations

  • Northwestern University

Tags

DTIC Thesaurus Topics

  • Biological Factors
  • Biological Markers
  • Biomedical Research
  • Blood
  • Breast Cancer
  • Chemistry
  • Data Analysis
  • Growth Factors
  • Health Services
  • Hormones
  • Measurement
  • Medical Personnel
  • Neoplasms
  • Peptide Growth Factors
  • Peptides
  • Quality Control
  • Risk Factors

Fields of Study

  • Medicine

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Oncology and Biomarker-Based Cancer Detection.
  • Psychometric Testing or Psychological Assessment.