Development of Reactive Topical Skin Protectants against Sulfur Mustard and Nerve Agents

Abstract

The purpose of the Phase I Research was to investigate the feasibility of using Nantek's unique reactive nanoparticle (RNP) adsorbents as the active ingredient in a skin cream system for the protection against exposure to sulfur mustard and nerve agents. The scope of the work included: (1) study of mimic reactions with a broad array of adsorbents; (2) new adsorbent formulation development; (3) adsorbent-cream compatibility studies; (4) prototype skin system testing; and (5) reaction studies with actual nerve and mustard agents. Overall technical feasibility was established with the following major findings include: (1) RNP adsorbents are highly reactive and in some instances nearly instantaneously destroyed VX and its mimics; (2) actual evidence of decomposition and not merely absorption was observed; (3) HD and its mimics are partially decomposed by the RNP adsorbents suggesting the need for further optimization of the adsorbent formulations in Phase II; and (4) the most efficient RNP adsorbents demonstrated chemical compatibility and reactivity when embedded in the selected base cream.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1997
Accession Number
ADB230946

Entities

People

  • Kenneth Klabunde

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Chemical Analysis
  • Chemical Engineering
  • Chemical Synthesis
  • Chemical Warfare Agents
  • Chemistry
  • Chlorides
  • Composite Materials
  • Cyanides
  • Dermatologic Agents
  • Materials
  • Materials Science
  • Metal Oxides
  • Mustard Agents
  • Nanoparticles
  • Nerve Agents
  • Spectra
  • Titanium Oxides

Readers

  • Analytical Chemistry
  • Civilian Systems Systems Program Capability Development and Upgrade Support Activity Expense and Pay Management.
  • Nanocomposite Materials Science

Technology Areas

  • Biotechnology