Near Infrared Spectral Determination of Human Tissue pH.

Abstract

The feasibility of noninvasive, transcutaneous, near infrared spectral measurement of tissue pH in humans was experimentally demonstrated in this Phase I SBIR program. A prototype near infrared spectrometer instrument was developed that allowed for measurement of deep tissue pH in the kidney areas of 28 normal male and female volunteers. changes in pH were artificially induced by hyper-ventilation and breath holding. Near infrared estimates of tissue pH values were compared with reference laboratory values of venous blood pH for 6 blood samples of each patient. Near infrared estimates of pH demonstrated an accuracy of +/-0.03 pH in comparison with reference laboratory values. A Phase II SBIR program is recommended to develop a portable, near infrared field instrument to measure human tissue pH in a battlefield combat casualty care or a civilian emergency medical environment.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1995
Accession Number
ADB231081

Entities

People

  • Kenneth J. Schlager

Tags

Communities of Interest

  • Sensors

DTIC Thesaurus Topics

  • Abstracts
  • Accuracy
  • Algorithms
  • Biomedical Research
  • Casualties
  • Chemical Compounds
  • Chemistry
  • Combat Casualty Care
  • Eye
  • Infrared Spectrometers
  • Instrumentation
  • Measurement
  • Medical Personnel
  • Pattern Recognition
  • Spectrometers
  • Spectrometry
  • Test Methods

Readers

  • Environmental Engineering
  • Optical Physics and Photonics.
  • Trauma Surgery or Emergency Medicine.