A Light Weight, Portable EPR Spectrometer for Tissue Oxygenation Measurement

Abstract

The aim of this project is to provide a reliable means to obtain fast, accurate, and repeated measurements of pO2, perfusion, pH, and potentially, nitrio oxide (NO) directly in tissues in patients in the LSTAT (Life Support for Trauma' and Transport) system in order to monitor their status and provide data for their active management. Our approach exploits the capabilities of in vivo EPR techniques to make such measurements. In Phase I we initiated the design studies for adapting our existing technology to a portable configuration and started the construction of a key component for the proposed use: the catheter/needle probe which will enable us to make the desired measurements at various depths as required for this use, using an EPR frequency of 0.5 to 1.2 GHz. During Phase II we will complete the design and then construct a spectrometer suitable for the described purposes. We also will adapt the existing techniques for measuring pO2, pH, effective perfusion, and NO, to the needs and constraints for making these measurements in patients within the LSTAT system.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1995
Accession Number
ADB231094

Entities

People

  • Peter J. Kannam

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Biomedical Research
  • Catheters
  • Construction
  • Construction Materials
  • Frequency
  • Health Care
  • Magnetic Fields
  • Magnetic Materials
  • Magnetic Resonance
  • Materials
  • Measurement
  • Paramagnetic Materials
  • Paramagnetic Resonance
  • Resonance
  • Resonators
  • Vascular Diseases

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  • Aerospace Test and Evaluation
  • Cardiovascular Physiology
  • Systems Analysis and Design