Prospective Analyses of Hormone Levels, Alcohol Intake, and Body Fat Distribution in Relation to Breast Cancer Risk

Abstract

This career development award is allowing me to increase my expertise in the area of hormones, hormonally-related factors and risk of breast cancer. I proposed to prospectively assess plasma hormone levels, alcohol use and body fat distribution in relation to breast cancer risk. In year one of the grant, I received laboratory results for 155 breast cancer cases and 310 matched controls from a case-control study nested within the prospective Nurses' Health Study. Several primary estrogens (estradiol BOTH FREE AND BOUND FRACTIONS, estrone, estrone sulfate) and androgens (testosterone, androstenedione, DHEA, DHEAS) and prolactin were assayed. Statistical analyses of these data are ongoing and a manuscript is being prepared. Additionally, I have begun the analyses of alcohol intake and risk of breast cancer.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1997
Accession Number
ADB231829

Entities

People

  • Susan E. Hankinson

Organizations

  • Brigham and Women's Hospital

Tags

DTIC Thesaurus Topics

  • Alcohol Consumption
  • Biomedical Research
  • Blood
  • Body Composition
  • Breast Cancer
  • Cellular Structures
  • Data Analysis
  • Diseases And Disorders
  • Estrogens
  • Health Services
  • Hormones
  • Information Science
  • Medical Personnel
  • Neoplasms
  • Risk Factors
  • Sex Hormones
  • Testosterone

Fields of Study

  • Medicine

Readers

  • Prostate Cancer Biology.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.