Physical Activity, Body Size, Intentional Weight Loss and Breast Cancer Risk: Fellowship
Abstract
This postdoctoral training award supports studies to describe elements of energy balance and breast cancer incidence. The modifying effect of early-life body size and weight change on associations between early-life physical activity and breast cancer risk was evaluated using extant data from a case-control study of breast cancer. Cases (n=6888) were identified through four state-wide cancer registries; controls (n=9529) were randomly selected from population lists. Results suggest that, in premenopausal women, the relation between early-life physical activity and breast cancer risk is similar across all strata of early-life body size and weight change. In postmenopausal women, results suggest that risk reduction associated with physical activity may be greatest in women who were heaviest at age 18, and in women who maintained a stable weight between age 18 and 5 years prior to diagnosis, independent of initial weight. Preliminary data were obtained on intentional weight loss and weight reduction methods from the successful addition of relevant questions to an on-going case-control study of breast cancer. Responses to these questions suggest small, but potentially important, differences between cases and controls regarding patterns of intentional weight loss, choice of weight reduction method, and amount of weight lost.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1998
- Accession Number
- ADB249638
Entities
People
- Suzanne M. Shoff
Organizations
- University of Wisconsin–Madison