Cell Proliferation, Cell Death, and Size Regulation

Abstract

The goal of this project was to isolate the pie gene from Drosophila Melanogaster and determine its function in cell death and cell survival. In the first year, we determined that pie mutations affected a 120kb region of Drosophila DNA. Now we have identified the specific transcription unit encoding pie function. The predicted PIE protein is a 600 amino acid polypeptide unrelated to other known proteins.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1999
Accession Number
ADB258768

Entities

People

  • Nicholas E. Baker

Organizations

  • Albert Einstein College of Medicine

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Amino Acids
  • Animals
  • Biomedical Research
  • Cell Physiological Processes
  • Cells
  • Coding
  • Computer Programs
  • Drosophila
  • Genetic Code
  • Genetic Structures
  • Genetics
  • Government Procurement
  • Governments
  • Mutations
  • Regulations
  • Sequence Analysis

Fields of Study

  • Biology

Readers

  • Molecular Genetics
  • Personnel Management and Statistics in the Military and Department of Defense