Methyl-Deficient Diets and Risks of Breast Cancer Among African-American Women: A Case-Control Study by Methylation Status of the ER Gene

Abstract

This is the second annual report of our research project entitled "Methyl-Deficient Diets and Risks of Breast Cancer Among African-American Women: A Case-Control Study by Methylation Status of the ER gene". During the period, the numbers of interviewed cases and I controls increased to 243 and 232, respectively. The number of collected tumor tissue specimens reached 177 and more specimens are being obtained. Collected tissue specimens were measured on estrogen receptor status. Most data collected have been entered and maintained timely. We also wrote and submitted a manuscript related to breast cancer research in African-American women. However, laboratory measurement of methylation status of the ER gene CpG islands has lagged based on a number of reasons, despite our endeavors. Generally, this project has progressed according to the statement of work. More efforts will be made on the measurement of methylation status.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1999
Accession Number
ADB258773

Entities

People

  • Kangmin Zhu

Organizations

  • Meharry Medical College

Tags

DTIC Thesaurus Topics

  • African Americans
  • Biomedical Research
  • Breast Cancer
  • Cancer
  • Cardiovascular Physiological Phenomena
  • Caucasians
  • Chemistry
  • Colon Cancer
  • Diseases And Disorders
  • Ethnic Groups
  • Genetics
  • Health Services
  • Hypertension
  • Materials
  • Medical Personnel
  • Neoplasms
  • Ventricular Dysfunction

Readers

  • Clinical Trial Research.
  • Gender and Food Studies
  • Molecular and genetic basis of cancer.