Interstitial Optical Diagnosis and Treatment of Breast Cancer

Abstract

Aim: development of optical techniques for diagnosis and treatment of breast cancer Breast tissue can be examined rapidly using Elastic Scattering Spectroscopy (spectral analysis of white light reflected from tissue). We collect paired optical and conventional histologic measurements from breast tissues to see if the optical data could provide a pathological diagnosis. Preliminary artificial intelligence analysis of optical data from 61 sites (breast and sentinel node), gave a promising sensitivity (57-100%) and specificity (85-100%) for detecting cancer. Therapy aims for complete ablation of small cancers using MR guided Interstitial Laser Photocoagulation (ILP). We have shown that ILP can ablate small cancers and that contrast enhanced MR can detect untreated areas of cancer as small as 2mm.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1999
Accession Number
ADB260288

Entities

People

  • Stephen Brown

Organizations

  • University College London

Tags

Communities of Interest

  • Advanced Electronics

DTIC Thesaurus Topics

  • Artificial Intelligence
  • Biomedical Research
  • Breast Cancer
  • Carcinoma
  • Computers
  • Diseases And Disorders
  • Elastic Scattering
  • Health Services
  • Measurement
  • Medical Personnel
  • Neoplasms
  • Optical Fibers
  • Optical Properties
  • Pattern Recognition
  • Scattering
  • Spectroscopy
  • Surgery

Fields of Study

  • Medicine
  • Physics

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Optical Physics and Photonics.

Technology Areas

  • AI & ML
  • Directed Energy