Visual Servoing for Optimization of Anticancer Drug Uptake in Human Breast Cancer Cells

Abstract

The purpose of this two-year IDEA proposal is to gather preliminary data that demonstrate the feasibility of a new class of in vitro drug response and chemosensitivity assays. Our objectives are to develop an instrument (a visual servoing optical microscope, or VSOM) in a stepwise fashion and gather preliminary data to aid future development of cell culture techniques and fluorescence assays. Our goal is to demonstrate the feasibility of using VSOM technology to analyze the heterogeneity and physiological characteristics of tumor cells from individual breast cancer patient biopsies.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1999
Accession Number
ADB260298

Entities

People

  • Daniel E. Callahan

Organizations

  • University of California, Berkeley

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Biopsy
  • Breast Cancer
  • Cell Line
  • Cells
  • Computer Programs
  • Computers
  • Culture Techniques
  • Fluorescence
  • Government Procurement
  • Governments
  • Graphical User Interface
  • Materials
  • Microscopes
  • Optimization
  • Software Development
  • Visual Servoing

Readers

  • Chemistry (specifically Chemical Fluorescence)
  • Oncology
  • Software Engineering