Tissue Engineering Initiative
Abstract
The Cleveland Clinic Foundation Tissue Engineering Initiative was proposed to initiate novel tissue engineering projects as a collaboration between connective tissue biochemists, bioengineers, prototype engineers, and physician researchers from the Department of Biomedical Engineering. The primary focus of these projects was to test applications of hylan gels (divinyl sulfone crosslinked, purified hyaluronan). Gels were formulated in-house, as well as evaluating specimens obtained from the Matrix Biology Institute. During the final year of this project, considerable effort was devoted to developing the technology to repeatably produce hylans with improved mechanical strength, as well as ways to improve cell attachment and proliferation on and within the gels. Significant improvement has been made in both of these areas over the results submitted in the 2000 and 2001 Annual Reports. However, hylan-cell composites have not yet been optimized for the described systems. Although funding for this award was not renewed, much of the research on these projects is ongoing. Any pertinent future publications arising from this continued work will be - submitted for inclusion with this report.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2002
- Accession Number
- ADB283958
Entities
People
- Vincent C. Hascall